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Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis

Notch signaling plays a crucial role in the development of colon cancer; targeting the Notch pathway may sensitize colon cancers to various adjuvant agents. The focus of our current study is to identify natural compounds that target Notch signaling and that might be beneficial for the prevention and...

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Detalhes bibliográficos
Main Authors: Koduru, Srinivas, Kumar, Raj, Srinivasan, Sowmyalakshmi, Evers, Mark B, Damodaran, Chendil
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041017/
https://ncbi.nlm.nih.gov/pubmed/20053782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0771
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