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Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer

The tumor necrosis factor (TNF) receptor super family comprises of members that induce two distinct signaling cascades, leading to either cell survival or apoptosis. However, in prostate cancer (PCa), TNF-mediated prosurvival signaling is the predominant pathway that leads to cell survival and resis...

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Detalhes bibliográficos
Main Authors: Srinivasan, Sowmyalakshmi, Kumar, Raj, Koduru, Srinivas, Chandramouli, Aaditya, Damodaran, Chendil
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813934/
https://ncbi.nlm.nih.gov/pubmed/19851870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-009-0416-9
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