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Inhibition of FGFR2 and FGFR1 increases cisplatin sensitivity in ovarian cancer

Fibroblast Growth Factors (FGFs) have been implicated in malignant transformation, tumor mitogenesis, angiogenesis and chemoresistance. The aim of this study was to determine which FGFs and FGFRs play functional roles in epithelial ovarian cancer. Restriction enzyme analysis of mRNA revealed that tr...

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Bibliografiske detaljer
Main Authors: Cole, Claire, Lau, Sin, Backen, Alison, Clamp, Andrew, Rushton, Graham, Dive, Caroline, Hodgkinson, Cassandra, McVey, Rhona, Kitchener, Henry, Jayson, Gordon C
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040972/
https://ncbi.nlm.nih.gov/pubmed/20595807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.5.12585
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