Heparan sulphate synthetic and editing enzymes in ovarian cancer

Several angiogenic growth factors including fibroblast growth factors 1 and 2 (FGF1 and FGF2) depend on heparan sulphate (HS) for biological activity. We previously showed that all cellular elements in ovarian tumour tissue synthesised HS but biologically active HS (i.e. HS capable of binding FGF2 a...

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Detalhes bibliográficos
Main Authors: Backen, A C, Cole, C L, Lau, S C, Clamp, A R, McVey, R, Gallagher, J T, Jayson, G C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359940/
https://ncbi.nlm.nih.gov/pubmed/17437011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603747
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