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CanScript, an 18-Base pair DNA sequence, boosts tumor cell-specific promoter activity: Implications for targeted gene therapy
Gene therapy protocols for the treatment of cancer often employ gene promoter sequences that are known to be overexpressed in specific tumor cell types relative to normal cells. These promoters, while specific, are often weakly active. It would be desirable to increase the activity of such promoters...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040857/ https://ncbi.nlm.nih.gov/pubmed/20798601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.9.13234 |
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