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MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms

BACKGROUND: Identifying the functional importance of the millions of single nucleotide polymorphisms (SNPs) in the human genome is a difficult challenge. Therefore, a reverse strategy, which identifies functionally important SNPs by virtue of the bimodal abundance across the human population of the...

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Detalhes bibliográficos
Main Authors: Affara, Muna, Dunmore, Benjamin J, Sanders, Deborah A, Johnson, Nicola, Print, Cristin G, Charnock-Jones, D Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040839/
https://ncbi.nlm.nih.gov/pubmed/21244711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-43
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