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Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis

O-linked N-acetylglucosamine transferase (OGT) catalyzes O-GlcNAc addition to numerous cellular proteins including transcription and nuclear pore complexes and plays a key role in cellular signaling. One differentially spliced isoform of OGT is normally targeted to mitochondria (mOGT) but is quite c...

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Hlavní autoři: Shin, Sang-Hoon, Love, Dona C., Hanover, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Vienna 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040817/
https://ncbi.nlm.nih.gov/pubmed/20824293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-010-0719-8
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