Secretion of Novel SEL1L Endogenous Variants Is Promoted by ER Stress/UPR via Endosomes and Shed Vesicles in Human Cancer Cells

We describe here two novel endogenous variants of the human endoplasmic reticulum (ER) cargo receptor SEL1LA, designated p38 and p28. Biochemical and RNA interference studies in tumorigenic and non-tumorigenic cells indicate that p38 and p28 are N-terminal, ER-anchorless and more stable relative to...

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Bibliographische Detailangaben
Hauptverfasser: Cattaneo, Monica, Lotti, Lavinia Vittoria, Martino, Simone, Alessio, Massimo, Conti, Antonio, Bachi, Angela, Mariani-Costantini, Renato, Biunno, Ida
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040770/
https://ncbi.nlm.nih.gov/pubmed/21359144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017206
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