Functional Characterization of Two Secreted SEL1L Isoforms Capable of Exporting Unassembled Substrate

SEL1L-A, a transmembrane glycoprotein residing in the endoplasmic reticulum (ER), is a component of the ER-associated degradation (ERAD) pathway. Alternative splicing generates two smaller SEL1L isoforms, -B and -C, that lack the SEL1L-A membrane-spanning region but retain some sel-1-like repeats, k...

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Detalhes bibliográficos
Main Authors: Cattaneo, Monica, Lotti, Lavinia Vittoria, Martino, Simone, Cardano, Marina, Orlandi, Rosaria, Mariani-Costantini, Renato, Biunno, Ida
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670146/
https://ncbi.nlm.nih.gov/pubmed/19204006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805408200
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