Behavioral Defects in Chaperone-Deficient Alzheimer's Disease Model Mice

Molecular chaperones protect cells from the deleterious effects of protein misfolding and aggregation. Neurotoxicity of amyloid-beta (Aβ) aggregates and their deposition in senile plaques are hallmarks of Alzheimer's disease (AD). We observed that the overall content of αB-crystallin, a small h...

Full description

Saved in:
Bibliographic Details
Main Authors: Ojha, Juhi, Karmegam, Rajalakshmi V., Masilamoni, J. Gunasingh, Terry, Alvin V., Cashikar, Anil G.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040748/
https://ncbi.nlm.nih.gov/pubmed/21379584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016550
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items