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Behavioral Defects in Chaperone-Deficient Alzheimer's Disease Model Mice
Molecular chaperones protect cells from the deleterious effects of protein misfolding and aggregation. Neurotoxicity of amyloid-beta (Aβ) aggregates and their deposition in senile plaques are hallmarks of Alzheimer's disease (AD). We observed that the overall content of αB-crystallin, a small h...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040748/ https://ncbi.nlm.nih.gov/pubmed/21379584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016550 |
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