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RhoA-mediated signaling up-regulates hepatocyte growth factor gene and protein expression in response to apoptotic cells

Clearance of apoptotic cells by macrophages induces HGF secretion. We examined the regulatory mechanisms of HGF mRNA and protein expression in macrophages upon exposure to apoptotic cells. The interaction of RAW 264.7 macrophages with apoptotic Jurkat cells, but not with viable cells, resulted in ex...

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Autors principals: Park, Hyun-Jung, Choi, Youn-Hee, Cho, Young Joo, Henson, Peter M., Kang, Jihee Lee
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040470/
https://ncbi.nlm.nih.gov/pubmed/21148681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0710414
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