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RhoA-mediated signaling up-regulates hepatocyte growth factor gene and protein expression in response to apoptotic cells

Clearance of apoptotic cells by macrophages induces HGF secretion. We examined the regulatory mechanisms of HGF mRNA and protein expression in macrophages upon exposure to apoptotic cells. The interaction of RAW 264.7 macrophages with apoptotic Jurkat cells, but not with viable cells, resulted in ex...

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Main Authors: Park, Hyun-Jung, Choi, Youn-Hee, Cho, Young Joo, Henson, Peter M., Kang, Jihee Lee
Format: Artigo
Jezik:Inglês
Izdano: Society for Leukocyte Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040470/
https://ncbi.nlm.nih.gov/pubmed/21148681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0710414
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