Blockade of AT1 Receptors Protects the Blood–Brain Barrier and Improves Cognition in Dahl Salt-Sensitive Hypertensive Rats

BACKGROUND: The present study tested the hypothesis that inappropriate activation of the brain renin–angiotensin system (RAS) contributes to the pathogenesis of blood–brain barrier (BBB) disruption and cognitive impairment during development of salt-dependent hypertension. Effects of an angiotensin...

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Main Authors: Pelisch, Nicolas, Hosomi, Naohisa, Ueno, Masaki, Nakano, Daisuke, Hitomi, Hirofumi, Mogi, Masaki, Shimada, Kenji, Kobori, Hiroyuki, Horiuchi, Masatsugu, Sakamoto, Haruhiko, Matsumoto, Masayasu, Kohno, Masakazu, Nishiyama, Akira
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040273/
https://ncbi.nlm.nih.gov/pubmed/21164491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2010.241
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