Blockade of AT1 Receptors Protects the Blood–Brain Barrier and Improves Cognition in Dahl Salt-Sensitive Hypertensive Rats

BACKGROUND: The present study tested the hypothesis that inappropriate activation of the brain renin–angiotensin system (RAS) contributes to the pathogenesis of blood–brain barrier (BBB) disruption and cognitive impairment during development of salt-dependent hypertension. Effects of an angiotensin...

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Autors principals: Pelisch, Nicolas, Hosomi, Naohisa, Ueno, Masaki, Nakano, Daisuke, Hitomi, Hirofumi, Mogi, Masaki, Shimada, Kenji, Kobori, Hiroyuki, Horiuchi, Masatsugu, Sakamoto, Haruhiko, Matsumoto, Masayasu, Kohno, Masakazu, Nishiyama, Akira
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040273/
https://ncbi.nlm.nih.gov/pubmed/21164491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2010.241
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