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Iron Loading-Induced Aggregation and Reduction of Iron Incorporation in Heteropolymeric Ferritin Containing a Mutant Light Chain that Causes Neurodegeneration
Hereditary Ferritinopathy (HF) is a neurodegenerative disease characterized by intracellular ferritin inclusion bodies (IBs) and iron accumulation throughout the central nervous system. Ferritin IBs are composed of mutant ferritin light chain as well as wild type light (Wt-FTL) and heavy chain (FTH1...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040265/ https://ncbi.nlm.nih.gov/pubmed/21029774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.10.010 |
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