Wegener's granulomatosis autoantibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils.

Anti-neutrophil cytoplasmic autoantibodies (ANCA) specifically associated with Wegener's granulomatosis were found to be directed against a saline-soluble glycoprotein triplet that migrates on SDS gels as distinct bands of Mr 29,000, 30,500, and 32,000 and is present in the azurophilic granules...

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Vydáno v:J Clin Invest
Hlavní autoři: Goldschmeding, R, van der Schoot, C E, ten Bokkel Huinink, D, Hack, C E, van den Ende, M E, Kallenberg, C G, von dem Borne, A E
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1989
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304024/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2681270/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114335
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