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Cell Origin and Culture History Determine Successful Integration of Neural Precursor Transplants into the Dentate Gyrus of the Adult Rat

The success of transplants of neural tissue into the adult dentate gyrus in generating mature neurons is highly variable. Here we address the roles of the origin of the tissue and its pre-implantation preparation, and show that both are critical. We transplanted neonatal cultured or primary rat cell...

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Autors principals: Chen, Xia, Tolkovsky, Aviva M., Herbert, Joe
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040198/
https://ncbi.nlm.nih.gov/pubmed/21359219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017072
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