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Modulation of CTCF insulator function by transcription of a non-coding RNA
CTCF plays diverse roles in the regulation of eukaryotic genes. A new study by Lefevre et al., 2008 reveals a novel mechanism in which non-coding RNA transcription and nucleosome repositioning evicts CTCF from a regulatory element, to facilitate induction of a nearby gene.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040117/ https://ncbi.nlm.nih.gov/pubmed/18854131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.09.013 |
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