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A CTCF Code for 3D Genome Architecture

The architectural protein CTCF plays a complex role in decoding the functional output of the genome. Guo et al. now show that the orientation of a CTCF site restricts its choice of interacting partner, thus creating a code that predicts the three-dimensional organization of the genome. We propose a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Nichols, Michael H., Corces, Victor G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745123/
https://ncbi.nlm.nih.gov/pubmed/26276625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.053
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