A regiospecific monooxygenase with novel stereopreference is the major pathway for arachidonic acid oxygenation in isolated epidermal cells.

We investigated the enzymatic mechanisms responsible for AA oxygenation in homogenous cell suspensions obtained by trypsinization of epidermis from healthy subjects. Cell incubation with AA (0.3-150 microM) invariably resulted in the predominant generation of a compound identified as 12-hydroxyeicos...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Holtzman, M J, Turk, J, Pentland, A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304008/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2509517/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114319
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