Chloride secretory response of cystic fibrosis human airway epithelia. Preservation of calcium but not protein kinase C- and A-dependent mechanisms.

Because the defect in Cl- secretion exhibited by cystic fibrosis (CF) epithelia reflects regulatory rather than conductive abnormalities of an apical membrane Cl- channel, we investigated the role of different regulatory pathways in the activation of Cl- secretion in freshly excised normal and CF na...

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Pubblicato in:	J Clin Invest
Autori principali:	Boucher, R C, Cheng, E H, Paradiso, A M, Stutts, M J, Knowles, M R, Earp, H S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304005/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2478586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114316
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