Chloride secretory response of cystic fibrosis human airway epithelia. Preservation of calcium but not protein kinase C- and A-dependent mechanisms.

Because the defect in Cl- secretion exhibited by cystic fibrosis (CF) epithelia reflects regulatory rather than conductive abnormalities of an apical membrane Cl- channel, we investigated the role of different regulatory pathways in the activation of Cl- secretion in freshly excised normal and CF na...

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Bibliographic Details
Main Authors: Boucher, R C, Cheng, E H, Paradiso, A M, Stutts, M J, Knowles, M R, Earp, H S
Format: Artigo
Language:Inglês
Published: 1989
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC304005/
https://ncbi.nlm.nih.gov/pubmed/2478586
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