EVIDENCE FOR MESENCHYMAL-LIKE SUBPOPULATIONS WITHIN SQUAMOUS CELL CARCINOMAS POSSESSING CHEMORESISTANCE AND PHENOTYPIC PLASTICITY

Variable drug responses among malignant cells within individual tumors may represent a barrier to their eradication using chemotherapy. Carcinoma cells expressing mesenchymal markers resist conventional and epidermal growth factor receptor (EGFR)-targeted chemotherapy. Here we evaluated whether mese...

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Autors principals: Basu, Devraj, Nguyen, Thierry-Thien K., Montone, Kathleen T., Zhang, Gao, Wang, Li-Ping, Diehl, J. Alan, Rustgi, Anil K., Lee, John T., Weinstein, Gregory S., Herlyn, Meenhard
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039880/
https://ncbi.nlm.nih.gov/pubmed/20498638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.170
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