Bicarbonate-dependent and -independent intracellular pH regulatory mechanisms in rat hepatocytes. Evidence for Na+-HCO3- cotransport.

Using the pH-sensitive dye 2,7-bis(carboxyethyl)-5(6)-carboxy-fluorescein and a continuously perfused subconfluent hepatocyte monolayer cell culture system, we studied rat hepatocyte intracellular pH (pHi) regulation in the presence (+HCO3-) and absence (-HCO3-) of bicarbonate. Baseline pHi was high...

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Bibliographic Details

Published in:	J Clin Invest
Main Authors:	Gleeson, D, Smith, N D, Boyer, J L
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 1989
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303984/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2544626/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114156
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