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Bicarbonate-dependent and -independent intracellular pH regulatory mechanisms in rat hepatocytes. Evidence for Na+-HCO3- cotransport.

Using the pH-sensitive dye 2,7-bis(carboxyethyl)-5(6)-carboxy-fluorescein and a continuously perfused subconfluent hepatocyte monolayer cell culture system, we studied rat hepatocyte intracellular pH (pHi) regulation in the presence (+HCO3-) and absence (-HCO3-) of bicarbonate. Baseline pHi was high...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Gleeson, D, Smith, N D, Boyer, J L
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303984/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2544626/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114156
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