A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis

BACKGROUND: The underlying mechanisms involved in the activation of hypoxia-inducible factor-1 (HIF-1) in gastric cancer remain unclear. As nuclear factor-κB (NF-κB) as well as HIF-1 have been implicated in angiogenesis of various cancers, we investigated their relationship in gastric cancer. METHOD...

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Autores principales: Nam, S Y, Ko, Y S, Jung, J, Yoon, J, Kim, Y H, Choi, Y J, Park, J W, Chang, M S, Kim, W H, Lee, B L
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
Materias:
Molecular Diagnostics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039796/
https://ncbi.nlm.nih.gov/pubmed/21119667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6606020
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