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Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression
BACKGROUND: TACE/ADAM17 is a transmembranous protease that cleaves membrane-bound growth factors like EGFR ligands. TACE-dependent proteolysis is regulated by its inhibitor, tissue inhibitor of metalloproteinases 3 (TIMP3). This study analyses the role of TACE and TIMP3 mRNA expression in squamous c...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039790/ https://ncbi.nlm.nih.gov/pubmed/21102583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6606017 |
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