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zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation

The treatment of L929 fibrosarcoma cells with zVAD has been shown to induce necroptosis. However, whether autophagy is involved or not in this event remains controversial. In this study, we re-examined the role of autophagy in zVAD-induced cell death in L929 cells and further elucidated the signalin...

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Detalhes bibliográficos
Main Authors: Chen, Szu-ying, Chiu, Ling-Ya, Maa, Ming-Chei, Wang, Jang-Shiun, Chien, Chung-Liang, Lin, Wan-Wan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039770/
https://ncbi.nlm.nih.gov/pubmed/21127402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.2.14212
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