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Synthetic substrates for measuring activity of autophagy proteases: Autophagins (Atg4)

Atg4 cysteine proteases (autophagins) play crucial roles in autophagy by proteolytic activation of Atg8 paralogs for targeting to autophagic vesicles by lipid conjugation, as well as in subsequent deconjugation reactions. However, the means to measure the activity of autophagins is limited. Herein,...

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書誌詳細
主要な著者: Shu, Chih-Wen, Drag, Marcin, Bekes, Miklos, Zhai, Dayong, Salvesen, Guy S, Reed, John C
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039740/
https://ncbi.nlm.nih.gov/pubmed/20818167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.7.13075
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