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Serine Phosphoacceptor Sites within the Core Protein of Hepatitis B Virus Contribute to Genome Replication Pleiotropically

The core protein of hepatitis B virus can be phosphorylated at serines 155, 162, and 170. The contribution of these serine residues to DNA synthesis was investigated. Core protein mutants were generated in which each serine was replaced with either alanine or aspartate. Aspartates can mimic constitu...

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Détails bibliographiques
Auteurs principaux: Lewellyn, Eric B., Loeb, Daniel D.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039676/
https://ncbi.nlm.nih.gov/pubmed/21358805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017202
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