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The Arginine Clusters of the Carboxy-Terminal Domain of the Core Protein of Hepatitis B Virus Make Pleiotropic Contributions to Genome Replication

The carboxy-terminal domain (CTD) of the core protein of hepatitis B virus is not necessary for capsid assembly. However, the CTD does contribute to encapsidation of pregenomic RNA (pgRNA). The contribution of the CTD to DNA synthesis is less clear. This is the case because some mutations within the...

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Detalhes bibliográficos
Main Authors: Lewellyn, Eric B., Loeb, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020508/
https://ncbi.nlm.nih.gov/pubmed/21084467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01957-10
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