ZIC1 Is Downregulated through Promoter Hypermethylation, and Functions as a Tumor Suppressor Gene in Colorectal Cancer

The transcription factor, Zinc finger of the cerebellum (ZIC1), plays a crucial role in vertebrate development. Recently, ZIC1 has also been found to participate in the progression of human cancers, including medulloblastomas, endometrial cancers, and mesenchymal neoplasms. However, the function of...

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Autors principals: Gan, Lihong, Chen, Shujie, Zhong, Jing, Wang, Xian, Lam, Emily K. Y., Liu, Xin, Zhang, Jianbin, Zhou, Tianhua, Yu, Jun, Si, Jianmin, Wang, Liangjing, Jin, Hongchuan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039653/
https://ncbi.nlm.nih.gov/pubmed/21347233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016916
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