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POTENTIAL APPLICATION OF GRAPE DERIVED POLYPHENOLS IN HUNTINGTON’S DISEASE

Huntington’s disease (HD) is a progressive neurodegenerative disorder associated with selective neuronal cell death. Abnormal aggregation of huntingtin protein with polyQ expansion has been shown to be causally linked to HD. Grape seed polyphenolic extract (GSPE) is a natural compound that has previ...

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Detalhes bibliográficos
Main Authors: Wang, Jun, Pfleger, Cathie M., Friedman, Lauren, Vittorino, Roselle, Zhao, Wei, Qian, Xianjuan, Conley, Lindsay, Ho, Lap, Pasinetti, Giulio M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039436/
https://ncbi.nlm.nih.gov/pubmed/21331299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/v10134-010-0022-y
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