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Grape-Seed Polyphenolic Extract Improves the Eye Phenotype in a Drosophila Model of Tauopathy

Drosophila models of tauopathies have been developed by transgenically overexpressing the disease-associated forms of tau. In this paper we report for the first time that a recently developed Grape-Seed Polyphenolic Extract (GSPE) improves the eye phenotype of a Drosophila eye model of R406W tau. GS...

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Hlavní autoři: Pfleger, Cathie M., Wang, Jun, Friedman, Lauren, Vittorino, Roselle, Conley, Lindsay M., Ho, Lap, Fivecoat, Hayley C., Pasinetti, Giulio M.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE-Hindawi Access to Research 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943075/
https://ncbi.nlm.nih.gov/pubmed/20871666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/576357
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