Class II Phosphoinositide 3-Kinase Regulates Exocytosis of Insulin Granules in Pancreatic β Cells

Phosphoinositide 3-kinases (PI3Ks) are critical regulators of pancreatic β cell mass and survival, whereas their involvement in insulin secretion is more controversial. Furthermore, of the different PI3Ks, the class II isoforms were detected in β cells, although their role is still not well understo...

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Detalhes bibliográficos
Main Authors: Dominguez, Veronica, Raimondi, Claudio, Somanath, Sangeeta, Bugliani, Marco, Loder, Merewyn K., Edling, Charlotte E., Divecha, Nullin, da Silva-Xavier, Gabriela, Marselli, Lorella, Persaud, Shanta J., Turner, Mark D., Rutter, Guy A., Marchetti, Piero, Falasca, Marco, Maffucci, Tania
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039383/
https://ncbi.nlm.nih.gov/pubmed/21127054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200295
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