Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides.

Adenylate cyclase in liver plasma membranes from streptozotocin-diabetic (STZ) or BB/Wor spontaneously diabetic rats showed increased responsiveness to GTP, glucagon, fluoroaluminate, and cholera toxin. Basal or forskolin-stimulated activity was unchanged in STZ rats, but increased in BB/Wor rats. N...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Lynch, C J, Blackmore, P F, Johnson, E H, Wange, R L, Krone, P K, Exton, J H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303930/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2498395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114116
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