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A quantitative assay for measuring mRNA decapping by splinted ligation reverse transcription polymerase chain reaction: qSL-RT-PCR

The degradation of messenger RNA is a critical node of gene regulation. A major pathway of mRNA decay is initiated by shortening of the poly(A) tail, followed by removal of the 5′ cap structure (decapping) and subsequent degradation. Decapping is an important determinate in the destruction of many t...

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Autori principali: Blewett, Nathan, Coller, Jeff, Goldstrohm, Aaron
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039152/
https://ncbi.nlm.nih.gov/pubmed/21220548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2436411
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