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A quantitative assay for measuring mRNA decapping by splinted ligation reverse transcription polymerase chain reaction: qSL-RT-PCR

The degradation of messenger RNA is a critical node of gene regulation. A major pathway of mRNA decay is initiated by shortening of the poly(A) tail, followed by removal of the 5′ cap structure (decapping) and subsequent degradation. Decapping is an important determinate in the destruction of many t...

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Bibliografiske detaljer
Main Authors: Blewett, Nathan, Coller, Jeff, Goldstrohm, Aaron
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039152/
https://ncbi.nlm.nih.gov/pubmed/21220548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2436411
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