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Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow.

Bisphosphonates inhibit bone resorption in vivo and in vitro by unknown mechanisms. The effect of bisphosphonates on the formation of osteoclasts from their mononuclear hematopoietic precursors was investigated using human long-term marrow cultures in which multinucleated cells form that express mos...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Hughes, D E, MacDonald, B R, Russell, R G, Gowen, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303914/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2524504/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114100
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