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Invariant Natural Killer T Cells Inhibit Autoreactive B Cells in a Contact- and CD1d-dependent Manner

Autoantibody production is a hallmark of autoimmune diseases such as lupus and rheumatoid arthritis. Accumulating evidence suggests a role of invariant natural killer T cells (iNKT) in their pathogenesis. Mechanisms underlying iNKT role in these diseases, however, remain unclear. Here, we show that...

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Detalhes bibliográficos
Main Authors: Yang, Jun-Qi, Wen, Xiangshu, Kim, Peter J., Singh, Ram Raj
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039137/
https://ncbi.nlm.nih.gov/pubmed/21209282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002373
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