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Alternative memory in the CD8 lineage

A prominent population of innate CD8(+) T cells develops in the thymus of several gene deficient mouse strains, including Itk, KLF2, CBP, and Id3. These cells have the phenotype and function of memory CD8(+) T cells, without previous exposure to antigen. Surprisingly, the cytokine IL-4 plays a key r...

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Autors principals: Lee, You Jeong, Jameson, Stephen C., Hogquist, Kristin A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039080/
https://ncbi.nlm.nih.gov/pubmed/21288770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2010.12.004
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