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PLZF(+) T cells regulate memory-like CD8(+) T cell development

Several gene deficiency models promote the development of “innate CD8(+) T cells” that have diverse TCRs, but display a memory phenotype and rapidly produce cytokines. We here demonstrate that similar cells develop in Kruppel-Like Factor 2 (KLF2) deficient mice. However, this is not due to intrinsic...

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Sonraí Bibleagrafaíochta
Main Authors: Weinreich, Michael A., Odumade, Oludare A., Jameson, Stephen C., Hogquist, Kristin A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051359/
https://ncbi.nlm.nih.gov/pubmed/20601952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1898
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