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Role of an isoform-specific substrate access channel residue in CO ligand accessibilities of neuronal and inducible nitric oxide synthase isoforms

The rates of the bimolecular CO rebinding to the oxygenase domains of inducible and neuronal NOS proteins (iNOSoxy and nNOSoxy, respectively) after photolytic dissociation have been determined by laser flash photolysis. The following mutants at the isoform-specific sites (murine iNOSoxy N115L and ra...

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Bibliografske podrobnosti
Main Authors: Feng, Changjian, Fan, Weihong, Ghosh, Dipak K., Tollin, Gordon
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039037/
https://ncbi.nlm.nih.gov/pubmed/21146639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.11.007
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