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Role of an isoform-specific substrate access channel residue in CO ligand accessibilities of neuronal and inducible nitric oxide synthase isoforms

The rates of the bimolecular CO rebinding to the oxygenase domains of inducible and neuronal NOS proteins (iNOSoxy and nNOSoxy, respectively) after photolytic dissociation have been determined by laser flash photolysis. The following mutants at the isoform-specific sites (murine iNOSoxy N115L and ra...

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Détails bibliographiques
Auteurs principaux: Feng, Changjian, Fan, Weihong, Ghosh, Dipak K., Tollin, Gordon
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039037/
https://ncbi.nlm.nih.gov/pubmed/21146639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.11.007
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