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CXCR4 Signaling Mediates Morphine-induced Tactile Hyperalgesia

Morphine and related compounds are the first line of therapy in the treatment of moderate to severe pain. Over time, individuals taking opioids can develop an increasing sensitivity to noxious stimuli, even evolving into a painful response to previously non-noxious stimuli (opioid-induced hyperalges...

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Autori principali: Wilson, Natalie M., Jung, Hosung, Ripsch, Matthew S., Miller, Richard J., White, Fletcher A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039030/
https://ncbi.nlm.nih.gov/pubmed/21193025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2010.12.014
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