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FFAT rescues VAPA-mediated inhibition of ER-to-Golgi transport and VAPB-mediated ER aggregation

The VAMP-associated proteins termed VAP are a small gene family of proteins characterised by the presence of an N-terminal major sperm protein (MSP) domain. The P56S mutation of the B isoform (VAPB) has been linked to late-onset amyotrophic lateral sclerosis (ALS8) and its expression causes formatio...

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Detalhes bibliográficos
Main Authors: Prosser, Derek C., Tran, Duvinh, Gougeon, Pierre-Yves, Verly, Carine, Ngsee, Johnny K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038994/
https://ncbi.nlm.nih.gov/pubmed/18713837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.028696
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