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Cholesterol Is Required for Efficient Endoplasmic Reticulum-to-Golgi Transport of Secretory Membrane Proteins

Although cholesterol is synthesized in the endoplasmic reticulum (ER), compared with other cellular membranes, ER membrane has low cholesterol (3–6%). Most of the molecular machinery that regulates cellular cholesterol homeostasis also resides in the ER. Little is known about how cholesterol itself...

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Bibliographic Details
Main Authors: Ridsdale, Andrew, Denis, Maxime, Gougeon, Pierre-Yves, Ngsee, Johnny K., Presley, John F., Zha, Xiaohui
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415298/
https://ncbi.nlm.nih.gov/pubmed/16452637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-02-0100
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