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The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing.

The human platelet alloantigens, PlA1 and PlA2, comprise a diallelic antigen system located on a component of the platelet fibrinogen receptor, membrane glycoprotein (GP) IIIa. Of the known platelet alloantigens, PlA1, which is carried by 98% of the caucasian population, appears to be the alloantige...

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Pubblicato in:J Clin Invest
Autori principali: Newman, P J, Derbes, R S, Aster, R H
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303891/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2565345/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114082
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