An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system.

The human Pena/Penb alloantigen system represents a naturally occurring polymorphism of human platelet membrane glycoprotein (GP) IIIa, and has previously been implicated in the onset of two important clinical syndromes, neonatal alloimmune thrombocytopenic purpura and posttransfusion purpura. To in...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Wang, R, Furihata, K, McFarland, J G, Friedman, K, Aster, R H, Newman, P J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443268/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1430225/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116084
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