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Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue

BACKGROUND: Genes subject to genomic imprinting are mono-allelically expressed in a parent-of-origin dependent manner. Each imprinted locus has at least one differentially methylated region (DMR) which has allele specific DNA methylation and contributes to imprinted gene expression. Once DMRs are es...

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Autors principals: Woodfine, Kathryn, Huddleston, Joanna E, Murrell, Adele
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038880/
https://ncbi.nlm.nih.gov/pubmed/21281512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-4-1
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